Direct and indirect effects of vaccines: Evidence from COVID-19
We estimate direct and indirect vaccine effectiveness, and assess how far the infection-reducing externality extends from the vaccinated, a key input to policy decisions. Our empirical strategy uses nearly universal microdata from a single state and relies on the six-month delay between 12- and 11 year-old COVID vaccine eligibility. Vaccination reduces cases by 80 percent, the direct effect. This protection spills over to close contacts, producing a household-level indirect effect about half as large as the direct effect. However, indirect effects do not extend to schoolmates. Our results highlight vaccine reach as an important aspect of policy towards infectious disease.
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Copy CitationSeth M. Freedman, Daniel W. Sacks, Kosali I. Simon, and Coady Wing, "Direct and indirect effects of vaccines: Evidence from COVID-19," NBER Working Paper 30550 (2022), https://doi.org/10.3386/w30550.Download Citation
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Published Versions
Seth Freedman & Daniel W. Sacks & Kosali Simon & Coady Wing, 2026. "Direct and Indirect Effects of Vaccines: Evidence from COVID-19," American Economic Journal: Applied Economics, American Economic Association, vol. 18(1), pages 1-43, January, DOI: 10.1257/app.20230717. citation courtesy of ![]()
Seth Freedman & Daniel W. Sacks & Kosali Simon & Coady Wing, 2026. "Direct and Indirect Effects of Vaccines: Evidence from COVID-19," American Economic Journal: Applied Economics, vol 18(1), pages 1-43.