TY - JOUR AU - David,Guy AU - Markowitz,Sara TI - Side Effects of Competition: the Role of Advertising and Promotion in Pharmaceutical Markets JF - National Bureau of Economic Research Working Paper Series VL - No. 17162 PY - 2011 Y2 - June 2011 UR - http://www.nber.org/papers/w17162 L1 - http://www.nber.org/papers/w17162.pdf N1 - Author contact info: Guy David The Wharton School University of Pennsylvania 202 Colonial Penn Center 3641 Locust Walk Philadelphia, PA 19104-6218 Tel: 215/573-5780 Fax: 215/573-2157 E-Mail: gdavid2@wharton.upenn.edu Sara Markowitz Department of Economics Emory University 1602 Fishburne Dr. Atlanta, GA 30322 Tel: (404) 712-8167 E-Mail: sara.markowitz@emory.edu AB - The extent of pharmaceutical advertising and promotion can be characterized by a balancing act between profitable demand expansions and potentially unfavorable subsequent regulatory actions. However, this balance also depends on the nature of competition (e.g. monopoly versus oligopoly). In this paper we model the firm’s behavior under different competitive scenarios and test the model’s predictions using a novel combination of sales, promotion, advertising, and adverse event reports data. We focus on the market for erectile dysfunction drugs as the basis for estimation. This market is ideal for analysis as it is characterized by an abrupt shift in structure, all drugs are branded, the drugs are associated with adverse health events, and have extensive advertising and promotion. We find that advertising and promotion expenditures increase own market share but also increase the share of adverse drug reactions. Competitors’ spending decreases market share, while also having an influence on adverse drug reactions. ER -