TY - JOUR AU - Jayachandran,Seema AU - Lleras-Muney,Adriana AU - Smith,Kimberly V. TI - Modern Medicine and the 20th Century Decline in Mortality: Evidence on the Impact of Sulfa Drugs JF - National Bureau of Economic Research Working Paper Series VL - No. 15089 PY - 2009 Y2 - June 2009 UR - http://www.nber.org/papers/w15089 L1 - http://www.nber.org/papers/w15089.pdf N1 - Author contact info: Seema Jayachandran Department of Economics Northwestern University 2001 Sheridan Road Evanston, IL 60208 Tel: (847) 491-4757 Fax: (847) 491-7001 E-Mail: seema@northwestern.edu Adriana Lleras-Muney Department of Economics 9373 Bunche Hall UCLA Los Angeles, CA 90095 Tel: 310/825-3925 Fax: NA E-Mail: alleras@ECON.UCLA.EDU Kimberly V. Smith Princeton, NJ E-Mail: KSmith@mathematica-mpr.com AB - This paper studies the contribution of sulfa drugs, a groundbreaking medical innovation in the 1930s, to declines in U.S. mortality. For several often-fatal infectious diseases, sulfa drugs represented the first effective treatment. Using time-series and difference-in-differences methods (with diseases unaffected by sulfa drugs as a comparison group), we find that sulfa drugs led to a 25 to 40 percent decline in maternal mortality, 17 to 36 percent decline in pneumonia mortality, and 52 to 67 percent decline in scarlet-fever mortality between 1937 and 1943. Altogether, they reduced mortality by 2 to 4 percent and increased life expectancy by 0.4 to 0.8 years. We also find that sulfa drugs benefited whites more than blacks. ER -